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Hongbing Shen , MD, PhD
Professor of Epidemiology
Dean of School of Public Health, Nanjing Medical University
Education
Ph.D in Epidemiology, Shanghai Medical University, Shanghai, P.R. China, 1999
M.Sc in Epidemiology, Nanjing Medical College, Nanjing, P.R. China, 1989
B.Med./Medical Diploma in Public Health, Nanjing Medical College, Nanjing, P.R. China, 1986
Research Interest
Epidemiology of Non-communicable Chronic Disease
Academic Appointment
Professor of Epidemiology, Department of Epidemiology & Biostatistics, Nanjing Medical University School of Public Health, Nanjing, China, 2002.12 -
Instructor, Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, U.S.A. 2001.7-2002.11
Visiting scientist, Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, U.S.A. 1999.11-2001.6
Associate Professor, Department of Epidemiology & Biostatistics, Nanjing Medical University School of Public Health, Nanjing, China, 1998-2002
Lecturer, Department of Epidemiology & Biostatictics, Nanjing Medical University School of Public Health, Nanjing, China, 1992-1997
Awards
AACR-NCI International Investigator Opportunity Grant. American Association for Cancer Research Program Committee of 2007 Annual Meeting, Los Angeles, CA, April, 2007
AACR-AFLAC Incorporated Scholar-in-Training Award, American Association for Cancer Research Program Committee of 2003 Annual Meeting, Toronto, Canada, April, 2003
Forth place award of oral presentation in annual conference of The Association of Chinese Bioscientists in North America, Texas Chapter, April, 2001
Third place of “Huo Ying-Dong” excellent young teacher award in universities and colleges in China, Department of Education of China, Dec., 2000.
One of the excellent key teachers of Jiangsu colleges and universities, Jiangsu, China, 1999.
Excellent papers prize of the forth academic conference of Jiangsu youth, Jiangsu, China, 1999.
First Award of lecture competition in meddle aged and young teachers of Nanjing Medical University.
Research Projects
Principal Investigator: Environmental-related gene SNPs and Cancer Susceptibility (Ministry of Science and Technology of China, Grant # 2002CB512902, 2002.1-2007.12，¥1,500,000)
Principal Investigator: Molecular epidemiological study on DNA repair and lung cancer susceptibility. (National Science Foundation of China, Grant # 30371240, 2004.1-2006.12, ¥200,000)
Principal Investigator: Molecular epidemiology of non-small cell lung cancer. (National Outstanding Youth Science Foundation of China, Grant # 30425001, 2005.1-2008.12, ¥1,400,000)
Principal Investigator: Molecular epidemiology of chemosesitivity of breast cancer.( Jiangsu Natural Science Foundation; Grant# BK2004145, 2005.1-2006.12，¥75,000)
Principal Investigator: Chemosesitivity and personalized therapy of cancer of reproductive system for female (Cultivation Fund of the Key Scientific and Technical Innovation Project，Ministry of Education of China; Grant #705023，2006.1-2008.12，¥600,000)
Principal Investigator: Gene-environment interaction of folate metabolism in gastric cancer. (National Science Foundation of China, Grant # 30271148, 2003.1-2005.12, ¥180,000)
Selected Papers
Wang L, Ke Q, Chen W, Wang J, Tan Y, Zhou Y, Hua Z, Ding W, Niu J, Shen J, Zhang Z, Wang X, Xu Y, Shen H. Polymorphisms of MTHFD, Plasma Homocysteine Levels, and Risk of Gastric Cancer in a High-Risk Chinese Population.Clin Cancer Res. 2007 Apr 15;13(8):2526-32.
Hu Z, Wang H, Shao M, Jin G, Sun W, Wang Y, Liu H, Wang Y, Ma H, Qian J, Jin L, Wei Q, Lu D, Huang W, Shen H. Genetic variants in MGMT and risk of lung cancer in Southeastern Chinese: a haplotype-based analysis. Hum Mutat. 2007 May;28(5):431-40. .
Jin G, Wang L, Chen W, Hu Z, Zhou Y, Tan Y, Wang J, Hua Z, Ding W, Shen J, Zhang Z, Wang X, Xu Y, Shen H.Variant alleles of TGFB1 and TGFBR2 are associated with a decreased risk of gastric cancer in a Chinese population. Int J Cancer. 2007 Mar 15;120(6):1330-5.
Huo X, Hu Z, Zhai X, Wang Y, Wang S, Wang X, Qin J, Chen W, Jin G, Liu J, Gao J, Wei Q, Wang X, Shen H. Common non-synonymous polymorphisms in the BRCA1 Associated RING Domain (BARD1) gene are associated with breast cancer susceptibility: a case-control analysis. Breast Cancer Res Treat. 2007 May;102(3):329-37.
Hu Z, Xu L, Shao M, Yuan J, Wang F, Wang Y, Yuan W, Qian J, Ma H, Wang Y, Liu H, Chen W, Yang L, Jin G, Huo X, Chen F, Jin L, Wei Q, Huang W, Lu D, Wu T, Shen H. Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the TFIIH complex and risk of lung cancer: a case-control analysis in a Chinese population. Cancer Epidemiol Biomarkers Prev. 2006, 15(7):1336-40.
Hu Z, Shao M, Yuan J, Xu L, Wang F, Wang Y, Yuan W, Qian J, Ma H, Wang Y, Liu H, Chen W, Yang L, Jin G, Huo X, Chen F, Jin L, Wei Q, Huang W, Lu D, Wu T, Shen H. Polymorphisms in DNA damage binding protein 2 (DDB2) and susceptibility of primary lung cancer in the Chinese: a case-control study. Carcinogenesis. 2006 Jul;27(7):1475-1480.
Ma H, Hu Z, Zhai X, Wang S, Wang X, Qin J, Chen W, Jin G, Liu J, Gao J, Wang X, Wei Q, Shen H. Joint effects of single nucleotide polymorphisms in P53BP1 and P53 on breast cancer risk in a chinese population. Carcinogenesis. 2006 Apr;27(4):766-71.
Ma H, Jin G, Hu Z, Zhai X, Chen W, Wang S, Wang X, Qin J, Gao J, Liu J, Wang X, Wei Q, Shen H. Variant genotypes of CDKN1A and CDKN1B are associated with an increased risk of breast cancer in Chinese women.Int J Cancer. 2006 Jun 27;119(9):2173-8.
Hu Z, Huo X, Lu D, Qian J, Zhou J, Chen Y, Xu L, Ma H, Zhu J, Wei Q, Shen H. Functional polymorphisms and their haplotypes of Matrix Metalloproteinase-9 predict risk of the occurrence and metastasis of primary lung cancer. Clinical Cancer Research，2005，11(15):5433-5439
Hu Z, Ma H, Lu D, Zhou J, Chen Y, Xu L, Zhu J, Huo X, Qian J, Wei Q, Shen H. A Novel Functional Polymorphism (T-77C) of DNA Repair Gene XRCC1 Is Associated with Risk of Lung Cancer in Relation to Tobacco Smoking. Pharmacogenetics and Genomics，2005，15(7):458-463
Shen H, Wang L, Spitz MR, Hong WK, Mao L, Wei Q. A Novel Polymorphism in Human Cytosine DNA-Methyltransferase-3B Promoter Is Associated with an Increased Risk of Lung Cancer. Cancer Res. 2002 Sep 1;62(17):4992-5.
Shen H, Sturgis EM, Khan SG, Qiao Y, Shahlavi T, Eicher SA, Xu Y, Wang X, Strom SS, Spitz MR, Kraemer KH, Wei Q. An intronic poly (at) polymorphism of the DNA repair gene XPC and risk of squamous cell carcinoma of the head and neck: a case-control study. Cancer Res. 2001, Apr 15;61(8):3321-5. |
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